![]() Components of cinnamon make insulin more efficient.Īnderson and colleagues 6 demonstrated that the in vitro insulin-potentiating activity found in cinnamon is present in the aqueous fraction. People with metabolic syndrome have adequate amounts of insulin but the insulin is not efficient. This is important from a human health standpoint because it results in increased insulin sensitivity and less insulin is required to have larger insulin effects. The effects of adding more of the aqueous extract of cinnamon appear similar to adding more insulin. 4 Furthermore, when compared to herbs, spices, and medicinal extracts for insulin-like or insulin-potentiating activity in an in vitro model, 5 aqueous cinnamon extracts (CE) potentiated insulin activity more than 20-fold, higher than any other compound tested at comparable dilutions. In 1990, we reported that compounds found in cinnamon have insulin-potentiating properties and may be involved in the alleviation of the signs and symptoms of diabetes and cardiovascular diseases related to insulin resistance and metabolic syndrome. This review is an update of previous reviews. ![]() ![]() 1 In addition, several studies have examined the effects of cinnamon on glucose, insulin, and lipid metabolism associated with metabolic syndrome, which are the focus of this review. A review of the safety and efficacy of cinnamon on antioxidant activity, Heliobacter pylori infection, activation of olfactory cortex and brain, oral candidiasis in human immunodeficiency virus, and chronic salmonellosis has been published. aromaticum) have a long history of uses as spices, flavoring agents, preservatives, and pharmaco-logical agents. In summary, components of cinnamon may be important in the alleviation and prevention of the signs and symptoms of metabolic syndrome, type 2 diabetes, and cardiovascular and related diseases.Ĭommon cinnamon ( Cinnamomum verum, C. However, not all studies have shown positive effects of cinnamon, and type and amount of cinnamon, as well as the type of subjects and drugs subjects are taking, are likely to affect the response to cinnamon. Human studies involving control subjects and subjects with metabolic syndrome, type 2 diabetes mellitus, and polycystic ovary syndrome all show beneficial effects of whole cinnamon and/or aqueous extracts of cinnamon on glucose, insulin, insulin sensitivity, lipids, antioxidant status, blood pressure, lean body mass, and gastric emptying. In vitro studies also show that components of cinnamon control angiogenesis associated with the proliferation of cancer cells. In addition, cinnamon has been shown to alleviate factors associated with Alzheimer's disease by blocking and reversing tau formation in vitro and in ischemic stroke by blocking cell swelling. Cinnamon has been shown to improve all of these variables in in vitro, animal, and/or human studies. ![]() Metabolic syndrome is associated with insulin resistance, elevated glucose and lipids, inflammation, decreased antioxidant activity, increased weight gain, and increased glycation of proteins.
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